1. 毕业设计（论文）的内容和要求

环氧大豆油是用大豆油经过氧化处理后制得的一种化工产品，是一种使用广泛的聚氯乙烯无毒增塑剂兼稳定剂。

同时，其环氧基团经开环后得到多元醇，可进一步用于润滑油或聚氨酯材料的制备。

由于反应原料中有双氧水，常规间歇釜式反应存在安全隐患，且产品品质一般；微流场技术在环氧大豆油的合成中具有安全、高效、高质、连续化等优势。

2. 参考文献

[1] Sun, L. J.; Yao, C.; Zheng, H. F.; Lin, J. A novel direct synthesis of polyol from soybean oil. Chin. Chem. Lett. 2012, 23 (8), 919-922. [2] Bandyopadhyay-Ghosh, S.; Ghosh, S. B.; Sain, M. Synthesis of soy-polyol by two step continuous route and development of soy-based polyurethane foam. J. Polym. Environ. 2010, 18 (3), 437-442. [3] Petrovi#263;, Z. S. Polyurethanes from vegetable oils. Polym. Rev. 2008, 48 (1), 109-155. [4] Yang, L. T.; Zhao, C. S.; Dai, C. L.; Fu, L. Y.; Lin, S. Q. Thermal and mechanical properties of polyurethane rigid foam based on epoxidized soybean oil. J. Polym. Environ. 2012, 20 (1), 230-236. [5] Hazmi, A. S. A.; Aung, M. M.; Abdullah, L. C.; Salleh, M. Z.; Mahmood, M. H. Producing Jatropha oil-based polyol via epoxidation and ring opening. Ind. Crop. Prod. 2013, 50, 563-567. [6] Desroches, M.; Escouvois, M.; Auvergne, R.; Caillol, S.; Boutevin, B. From vegetable oils to polyurethanes: synthetic routes to polyols and main industrial products. Polym. Rev. 2012, 52 (1), 38-79. [7] Gu, R.; Konar, S.; Sain, M. Preparation and characterization of sustainable polyurethane foams from soybean oils. J. Am. Oil Chem. Soc. 2012, 89 (11), 2103-2111. [8] Rojek, P.; Prociak, A. Effect of different rapeseed-oil-based polyols on mechanical properties of flexible polyurethane foams. J. Appl. Polym. Sci. 2012, 125 (4), 2936-2945. [9] He, W.; Fang, Z.; Ji, D.; Chen, K.; Wan, Z.; Li, X.; Gan, H.; Tang, S.; Zhang, K.; Guo, K. Epoxidation of soybean oil by continuous micro-flow system with continuous separation. Org. Process Res. Dev. 2013, 17 (9), 1137-1141. [10] Schwalbe, T.; Autze, V.; Hohmann, M.; Stirner, W. Novel innovation systems for a cellular approach to continuous process chemistry from discovery to market. Org. Process Res. Dev. 2004, 8 (3), 440-454. [11] Watts, P.; Wiles, C. Micro reactors, flow reactors and continuous flow synthesis. J. Chem. Res. 2012, 36 (4), 181-193. [12] Kawaguchi, T.; Miyata, H.; Ataka, K.; Mae, K.; Yoshida, J. Room-temperature Swern oxidations by using a microscale flow system. Angew. Chem. Int. Ed. 2005, 44 (16), 2413-2416. [13] Serra, C. A.; Cortese, B.; Khan, I. U.; Anton, N.; Croon, M. H. J. M.; Hessel, V.; Ono, T.; Vandamme, T. Coupling microreaction technologies, polymer chemistry, and processing to produce polymeric micro and nanoparticles with controlled size, morphology, and composition. Macromol. React. Eng. 2013, 7 (9), 414-439. [14] Zhu, X. Determination of hydroxyl value of epoxy-containing polyester by acetyl chloride method. Chem. Propell. Polym. Mater. 2007, 5 (1), 65-66. [15] Guo, Y.; Hardesty, J. H.; Mannari, V. M.; Massingill, J. L. Hydrolysis of epoxidized soybean oil in the presence of phosphoric acid. J. Am. Oil Chem. Soc. 2007, 84 (10), 929-935. [16] Ji, D.; Fang, Z.; Wan, Z. D.; Chen, H. C.; He, W.; Li, X. L.; Guo, K. Rigid polyurethane foam based on modified soybean oil. Adv. Mater. Res. 2013, 724-725, 1681-1684. [17] Wu, S.; Soucek, M. D. Oligomerization mechanism of cyclohexene oxide. Polymer 1998, 39 (15), 3583-3586. [18] Tu, Y. C.; Suppes, G. J.; Hsieh, F. H. Thermal and mechanical behavior of flexible polyurethane-molded plastic films and water-blown foams with epoxidized soybean oil. J. Appl. Polym. Sci. 2009, 111 (3), 1311-1317. [19] Luo, X.; Mohanty, A.; Misra, M. Lignin as a reactive reinforcing filler for water-blown rigid biofoam composites from soy oil-based polyurethane. Ind. Crop. Prod. 2013, 47, 13-19. [20] Pan, X.; Saddler, J. N. Effect of replacing polyol by organosolv and kraft lignin on the property and structure of rigid polyurethane foam. Biotechnol. Biofuels 2013, 6, DOI 10.1186/1754-6834-6-12. [21] Lee, C. S.; Ooi, T. L.; Chuah, C. H.; Ahmad, S. Rigid polyurethane foam production from palm oil-based epoxidized diethanolamides. J. Am. Oil Chem. Soc. 2007, 84 (12), 1161-1167. [22] Tu, Y. C.; Kiatsimkul, P.; Suppes, G.; Hsieh, F. H. Physical properties of water-blown rigid polyurethane foams from vegetable oil-based polyols. J. Appl. Polym. Sci. 2007, 105 (2), 453-459. [23] Tan, S.; Abraham, T.; Ference, D.; Macosko, C. W. Rigid polyurethane foams from a soybean oil-based polyol. Polymer 2011, 52 (13), 2840-2846. [24] Zhang, C.; Ding, R.; Kessler, M. R. Reduction of epoxidized vegetable oils: a novel method to prepare bio-based polyols for polyurethanes. Macromol. Rapid Commun. 2014, 35 (11), 1068-1074.

3. 毕业设计（论文）进程安排

起讫日期 设计（论文）各阶段工作内容 1.1-1.15 确定毕业设计的课题及相关资料的查找 2.22-3.10 实验方案的设计 3.10-3.20 实验材料的准备 3.21-5.10 工艺合成 5.10-6.5 实验数据处理与结果分析 5.20-6.10 毕业论文书写