Aβ靶向性荧光螯合剂的合成与性质研究任务书
2020-06-08 21:17:54
1. 毕业设计(论文)的内容和要求
论文内容: 阿尔兹海默症(ad)是一种渐进的神经退行性紊乱疾病,它主要发生在老年人群中。
ad的病理学特征主要是β-淀粉样蛋白(aβ)的聚集,其聚集体毒性被一致认为是导致ad的主要原因。
金属离子如zn2 和cu2 在aβ的聚集过程中起了很重要的作用,它们稳固地结合到aβ上并导致多肽的成核最终聚集。
2. 参考文献
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3. 毕业设计(论文)进程安排
2016.12.1-2017.1.17查阅相关文献撰写开题报告 2017.1.1-2017.1.25完成外文文献翻译 2017.2.1-2017.2.15 实验前期准备(包括所需试剂原料、实验耗材的采购) 2017.2.15-2017.3.15荧光螯合剂的设计、合成与表征 2017.3.15-2017.4.15荧光螯合剂的合成、表征及荧光性质测试 2017.4.15-2017.6.7实验数据处理并撰写毕业论文