1. 毕业设计（论文）的内容和要求

本课题要求熟悉基本的理论知识，了解检测症状是否得到缓解的指标，进一步验证爱康胶囊在癌症康复中的临床疗效，严格遵循临床试验方案对病人进行临床试验观察。

每个病例与给药前一天、治疗期间、疗程结束后两天内由观察者将病人的主要症状及各项指标检测按照相关标准进行判定，并及时进行个体病症疗效与安全性总结，并严格填写病例报告表。

2. 参考文献

1. Yong Li, Dajiang Li, Jian Chen, Shuguang Wang, A polysaccharide from Pinellia ternata inhibits cell proliferation and metastasis in human cholangiocarcinoma cells by targeting of Cdc42 and 67 kDa Laminin Receptor (LR), International Journal of Biological Macromolecules, 2016,93:520#8211;525 2. Juntao Yin, Yantao hou, Yuyun Yin, Xiaoyong song, selenium-coated nanostructured lipid carriers used for oral delivery of berberine to accomplish a synergic hypoglycemic effect, International Journal of Nanomedicine, 2017(12): 8671#8211;8680 3. Radhika Kapoor, Shruti Singh, Madhulika Tripathi, Priyanka Bhatnagar, Poonam Kakkar1*, Kailash Chand Gupta, O-Hexadecyl-Dextran Entrapped Berberine Nanoparticles Abrogate High Glucose Stress Induced Apoptosis in Primary Rat Hepatocytes. Plosone, 2014,9(2 ): e89124

3. 毕业设计（论文）进程安排

1. 实验方案确定：2018.2.20-2018.3.1 2. 志愿者招募：2018.3.1-2018.3.10 3. 方案实施，疗效观察，收集数据：2018.3.10-2018.5.10 4. 毕业论文撰写及答辩：2018.5.10-2018.6