1. 毕业设计（论文）的内容和要求

聚多巴胺(pda)是贝壳、蚌等生物分泌的粘性蛋白的主要成分，具有极强的粘附性，能稳定地固定在各种基质上。虽然多巴胺在材料表面超强附着的作用机理还有待于进一步的研究，但已有研究表明，多巴胺对基体材料表面的附着行为来源于多巴胺的邻苯二酚和氨基官能团，这种结构可以和有机无机表面建立共价和非共价的相互作用，从而使聚多巴胺强力附着在材料表面上。

磷酸钙是无机硬组织的组成成分，它具有良好的生物性能，常被用来制备各种形貌的生物材料，而球形材料比其它材料具有更好的流动性、填充性和较大的比表面积。两者复合可以增强其稳定性能、生物相容性及机械强度。因此本实验目的为制备多孔并具有应用价值的聚多巴胺/磷酸钙复合微球，且稳定性好，生物活性好。同时实验中研究反应时间、反应温度对产物的影响，最后探索了磷酸钙复合微球的形成机制及制备。

本课题拟将聚多巴胺以自组装的方法包裹在碳酸钙微球表面形成复合微球，再以其为模板使用pbs矿化为磷酸钙复合微球。

2. 参考文献

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3. 毕业设计（论文）进程安排