1. 毕业设计（论文）的内容和要求

论文的数据必须实事求是。

通过论文将自己的实验结果通过图表、文字分析等步骤，按照逻辑方式得出结论。

要求论文的图表规范，文字表达清晰流畅，论文文字总数达到本科论文规定要求。

2. 参考文献

[1] Anthony K.Antimicrobial resistance will kill 300 million by 2050 without action [EB/OL].[2018-5-12].https://www.chemistryworld.com/news/antimicrobial-resistance-will-kill-300-million-by-2050-without-action/8086.article. [2] Oberl#233; K, Capdeville M J, Berthe T, et al. Evidence for a complex relationship between antibiotics and antibiotic-resistant Escherichia coli: from medical center patients to a receiving environment [J]. Environmental Science amp; Technology, 2012, 46(3):1859. [3] Storteboom H, Arabi M, Davis J G, et al. Identification of Antibiotic-Resistance-Gene Molecular Signatures Suitable as Tracers of Pristine River, Urban, and Agricultural Sources [J]. Environmental Science amp; Technology, 2010, 44(6):1947-1953. [4] Da Costa M P, Vaz-pires P, Bernardo F. Antimicrobial resistance in enterococcus spp. isolated in inflow,effluent and sludge from municipal sewage water treatment plants [J].Water Research,2006,40(8): 1735-1740. [5] 江月,陈奕涵,何义亮.长江下游某水源型水库抗生素抗性基因污染研究[J/OL].环境科学学报:1-11[2018-03-07].https://doi.org/10.13671/j.hjkxxb.2017.0385. [6] Parvathi A, Vijayan J, Murali G, et al. Comparative virulence genotyping and antimicrobial susceptibility profiling of environmental and clinical Salmonella enterica from Cochin, India.[J]. Current Microbiology, 2011, 62(1):21. [7] Liu Y Y, Wang Y, Walsh T R, et al. Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study [J]. Lancet Infectious Diseases, 2016, 16(2):161. [8] Ahammad Z S, Sreekrishnan T R, Hands C L, et al. Increased waterborne blaNDM-1 resistance gene abundances associated with seasonal human pilgrimages to the upper ganges river [J]. Environmental Science amp; Technology, 2014, 48(5):3014-3020.

3. 毕业设计（论文）进程安排

起讫日期 设计（论文）各阶段工作内容 备 注 查找收集文献资料、撰写开题报告 2周 准备实验器材和实验药品 2周 实验阶段 8周 处理数据、撰写论文 5周 答辩 1周