1. 毕业设计（论文）的内容和要求

1、毕业论文内容 二甘醇二苯甲酸酯（diethylene glycol dibenzoate，简称dedb），又称一缩二乙二醇双苯甲酸酯，是当前一种重要的新型环保型催化剂，具有广泛的用途。

目前dedb的合成方法主要以苯甲酸和二甘醇为原料，在催化剂作用下直接酯化合成dedb，其技术的关键是催化剂的使用。

传统合成方法以浓硫酸为催化剂，存在生产环境压力大且产品质量难以保证等问题，因此研究开发新型催化剂，开发debe绿色合成工艺具有重要的实际应用价值。

2. 参考文献

[1] Khorshidi A, Shariati S. Efficient synthesis of 3, 3#8217;-bisindoles Catalyzed by Fe3O4@MCM-48-OSO3H magnetic core-shell nanoparticles[J]. Chinese Journal of Catalysis, 2015, 36(5): 778-784. [2] Yoon S Y, Park Y S, Lee J S. Local liquid phase deposition of silicon dioxide on hexagonally close-packed silica beads[J]. Langmuir, 2015, 31(1): 249-253. [3] Golshekan M, Shariati S, Saadatjoo N. The synthesis of aminonaphtols and β-amino carbonyls in the presence of a magnetic recyclable Fe3O4@MCM-48-NaHSO4 nano catalyst[J]. RSC Advances, 2014, 4: 16589-16596. [4] Jackson D H K, Wang D, Gallo J M R, et al. Amine catalyzed atomic layer deposition of (3-Mercaptopropyl)trimethoxysilane for the production of heterogeneous sulfonic acid catalysts[J]. Chemistry of Materials, 2013, 25(19): 3844-3851. [5] Chang T, He L Q, Zhang X J, et al. Brouml;nsted acid surfactant-combined dicationic ionic liquids as green catalysts for biodiesel synthesis from free fatty acids and alcohols[J].Chinese Journal of Catalysis, 2015, 36(7): 982-986. [6] Jing H W, Wang X M, Liu Y, et al. Preparation of magnetic nanocomposites of solid acid catalysts and their applicability in esterification[J]. Chinese Journal of Catalysis, 2015, 36(2): 244-251. [7] Wu T, Wan J W, Ma X B, et al. Aqueous asymmetric aldol reaction catalyzed by nanomagnetic solid acid SO42-/Zr(OH)4-Fe3O4[J]. Chinese Journal of Catalysis, 2015, 36(3): 425-431. [8] Pirez C, Caderon J M, Dacquin J P, et al. Tunable KIT-6 mesoporous sulfonic acid catalysts for fatty acid esterification[J]. ACS Catalysis, 2012, 2(8): 1607-1614. [9] Morales G, Melero J A, Paniagua M, et al. Sulfonic acid heterogeneous catalysts for dehydration of C6-monosaccharides to 5-hydroxymethylfurfural in dimethyl sulfoxide[J]. Chinese Journal of Catalysis, 2014, 35(5): 644-655. [10] Ziarani G M, Lashgari N, Badiei A. Sulfonic acid-functionalized mesoporous silica (SBA-Pr-SO3H) as solid acid catalyst in organic reactions[J]. Journal of Molecular Catalysis A: Chemical, 2015, 397: 166-191.

3. 毕业设计（论文）进程安排

起讫日期 设计（论文）各阶段工作内容 2016.1-2016.2 完成文献检索和开题报告 2016.1-2016.2 建立产物的液相色谱分析方法 2016.3-016.4 合成固相催化剂并进行表面修饰改性，筛选高效催化剂，并通过结构表征对构效关系进行初步解析 2016.4-2016.5 催化工艺条件优化，产品的纯化分离和波谱学表征 2016.6 数据整理、论文写作和答辩