1. 毕业设计（论文）的内容和要求

二茂铁很容易进行取代反应，使人们对制备桥联二茂铁（二茂铁环蕃）的兴趣大大增加。

作为氧化还原中心，二茂铁又可以在多数溶液中经过多次可逆的单电子氧化还原反应，是一种理想的氧化还原修饰基团。

本小组近年来一直致力于研究将具有电化学活性的二茂铁与具有特殊性质的刚性基团及其衍生物相结合,得到同时具有光、电活性的超分子识别受体。

2. 参考文献

[1] 崔小明. 化学工业与工程技术,2000,21,6. [2] 杨庆华,叶宪曾,陶家洵. 二茂铁单羧基衍生物/Nafion修饰电极对多巴胺的电化学催化研究. 北京大学学报,1999,35(6),738. [3] 袁耀峰,叶素明,张蕴文. 具有生（物）理活性的二茂铁衍生物[J]. 化学通报，1995(5),24. [4] 韩前伟,朱晓晴,胡旭波. 二茂铁类环肽的合成与分子识别研究[J]. 高等学校化学学报,2002,23(11),2076. [5] 徐春,蔡宏,何品刚. 二茂铁标记DNA电化学探针的研制及性质研究[J]. 高等学校化学学报,2001,22(9),492. [6] 李纲.侯红卫.李林科. 二茂铁单甲酸根桥联的镧二聚体的合成,晶体结构及电化学性质[J]. 化学学报，2004，629(11),1060. [7] BACKTG. Organoselenium chemistry-practical approach [M]. Oxford: Oxford University Press, 1999. [8] RUAN Ming-de, ZHAO Hua-rong, ZHOU Xunjun. First example of selenium transfer reaction of primary selenoamides and selenourea. Novel synthesis of dialkyl diselenides from alkyl halides [J]. J. Organomet.Chem., 1995, 485(1), 19-24. [9] DEGRANDC, NOURM. Electrochemical reduction of seleniuminaprotic solvents: application to the selective electro synthesisof dialkyl selenides and/or diselenides [J]. J. Electroanal. Chem., 1985, 190(1/2), 213-223. [10] DEGRAN DC, PRESTR. Direct electrochemical synthesis of symmetrical aromatic diselenides and ditellurides by SNR substitution using Se and Te electrodes [J]. J. Electroanal Chem., 1991, 282(1), 281-286. [11] GAUTIERCT, DEGRANDC. Direct electrochemical synthesis of diaryl dichalcogenides by SRN1 reactions, using sacrificial selenium and tellurium cathodes [J]. J. Org. Chem., 1991, 56(19), 5703-5707. [12] BARTONDHR, FONTANAG. The invention of radical reaction-a convenient radical synthesis of dialkyl diselenides from carboxylic acids [J]. Tetrahedron, 1996, 52(34), 11163-11176. [13] KRIEFA, DEMAHIEUAF, DUMONTW. Efficient synthesis of diselenides from selenols [J]. Synthesis, 1988, 2(1), 131-133. [14] ZHONG Ping, GUO Meng-ping. Preparation of diselenides by the oxidation of selenols using trichloroisocyanuric acid [J]. Synth. Commun. , 2001, 31 (10), 1507-1510. [15] COHENVI. A new and simple synthesis of alkyl, cycloalkyl and aralkyl diselenides from aliphatic or aromatic aldehydes or aliphatic or cycloaliphatic ketones [J]. J. Org. Chem., 1977, 42(14), 2510-2511. [16] Zniber R, Moussaif A, Achour R. Preparation of macromolecules derived form benzimidazole [J]. Annales pharmaceutiques Francaises, 2002, 60(5), 345-347. [17] 李敏.有机化学[M]. 2006, 26, 2, 183-193. [18] (a)Graham P. J, Lindsey R. V, Parshall G. W, eta. lSom eacy l ferrocenes and their reac tion[J],J.Am.Chem.Soc,1957,79(13),3416 -3420.(b)霍宁.有机合成手册[M],北京科技出版社,1981,P59 - 60.

3. 毕业设计（论文）进程安排

见附件。