1. 毕业设计（论文）的内容和要求

玉米蛋白在包封化合物上被认为是一种非常有前景的材料。

但玉米蛋白纳米颗粒容易聚集并且对某些环境应力敏感，如接近等电点（pI = 6.2）的pH值、高离子强度和高温条件下不稳定，还有玉米蛋白纳米颗粒还表现出低包封率和负载效率较低的情况，本课题选择不同的多糖来制备蛋白-多糖反应共聚物，研究其共聚物的储藏稳定性。

2. 参考文献

[1] Luo Y, Wang Q. Zein‐based micro‐and nano‐particles for drug and nutrient delivery: A review[J]. Journal of Applied Polymer Science, 2014, 131(16). [2] Paliwal, Rishi, and Srinath Palakurthi. "Zein in controlled drug delivery and tissue engineering." Journal of Controlled Release 189 (2014): 108-122. [3] Hu D, Lin C, Liu L, et al. Preparation, characterization, and in vitro release investigation of lutein/zein nanoparticles via solution enhanced dispersion by supercritical fluids[J]. Journal of Food Engineering, 2012, 109(3): 545-552. [4] SUN L, SHEN P, ZHAO Y. Preparation of Resveratrol-loaded Zein Nanoparticles by Method of Supercritical CO_2 Anti-solvent Technology [J][J]. Fine Chemicals, 2011, 3: 014. [5] Patel A, Hu Y, Tiwari J K, et al. Synthesis and characterisation of zein#8211;curcumin colloidal particles[J]. Soft Matter, 2010, 6(24): 6192-6199. [6] Dai L, Sun C, Wei Y, et al. Characterization of Pickering emulsion gels stabilized by zein/gum arabic complex colloidal nanoparticles[J]. Food Hydrocolloids, 2018, 74: 239-248. [7] Hu K, McClements D J. Fabrication of biopolymer nanoparticles by antisolvent precipitation and electrostatic deposition: Zein-alginate core/shell nanoparticles[J]. Food Hydrocolloids, 2015, 44: 101-108. [8] Chang C, Wang T, Hu Q, et al. Pectin coating improves physicochemical properties of caseinate/zein nanoparticles as oral delivery vehicles for curcumin[J]. Food Hydrocolloids, 2017, 70: 143-151. [9] Soltani, Sahar, and Ashkan Madadlou. "Two-step sequential cross-linking of sugar beet pectin for transforming zein nanoparticle-based Pickering emulsions to emulgels." Carbohydrate polymers 136 (2016): 738-743. [10] 王丽娟. 玉米醇溶蛋白胶体颗粒的制备及应用研究[D]. 华南理工大学, 2014. [11] Cheng C J, Jones O G. Stabilizing zein nanoparticle dispersions with ι-carrageenan[J]. Food Hydrocolloids, 2017, 69: 28-35. [12] Zou L, Zhang Z, Zhang R, et al. Encapsulation of protein nanoparticles within alginate microparticles: Impact of pH and ionic strength on functional performance[J]. Journal of Food Engineering, 2016, 178: 81-89. [13] Liu F, Li R, Mao L, et al. Ethanol-induced composite hydrogel based on propylene glycol alginate and zein: Formation, characterization and application[J]. Food Chemistry, 2018. [14] Dons#236; F, Voudouris P, Veen S J, et al. Zein-based colloidal particles for encapsulation and delivery of epigallocatechin gallate[J]. Food Hydrocolloids, 2017, 63: 508-517. [15] Zhong Q, Jin M. Zein nanoparticles produced by liquid#8211;liquid dispersion. Food Hydrocoll 2009;23:2380#8211;7. [16] Patel A R, Velikov K P. Zein as a source of functional colloidal nano- and microstructures[J]. Current Opinion in Colloid Interface Science, 2014, 19(5):450-458.

3. 毕业设计（论文）进程安排

1. 2017.12-2018.2 查阅相关课题资料，撰写开题报告； 2. 2018.3-2018.5 确定实验方案、准备实验材料，并开展相关课题试验； 3. 2018.5-2018.6 对实验结果进行整理分析，撰写论文；