1. 毕业设计（论文）的内容和要求

探索在pH6.5~7.5范围内聚合多巴胺，对大肠杆菌进行包裹，获得高催化活性的固定化大肠杆菌。

并在此基础上进行改性，获得其它非自然特性，以应对不同的催化需求。

2. 参考文献

[1] Wang L , Hu Z Y , Yang X Y , et al. Polydopamine nanocoated whole-cell asymmetric biocatalysts[J]. Chemical Communications, 2017, 53. [2] Control of Microbial Growth in Alginate/Polydopamine Core/Shell Microbeads[J]. Chemistry - An Asian Journal, 2015, 10(10):2130-2133. [3] Geng W , Wang L , Jiang N , et al. Single cells in nanoshells for the functionalization of living cells[J]. Nanoscale, 2018, 10. [4] Wang J , Li B , Li Z , et al. Electropolymerization of dopamine for surface modification of complex-shaped cardiovascular stents[J]. Biomaterials, 2014, 35(27):7679-7689. [5] Interfacial Polymerization of Dopamine in a Pickering Emulsion: Synthesis of Cross-Linkable Colloidosomes and Enzyme Immobilization at Oil/Water Interfaces[J]. ACS Applied Materials Interfaces, 2015, 7(27):14954-14964. [6] Li F , Yu Y , Wang Q , et al. Polymerization of dopamine catalyzed by laccase: Comparison of enzymatic and conventional methods[J]. Enzyme and Microbial Technology, 2018, 119:58-64. [7] Yanqin F , Xiang L , Ruijie Y . The Surface Modification Methods for Constructing Polymer-Coated Stents[J]. International Journal of Polymer Science, 2018, 2018:1-7.

3. 毕业设计（论文）进程安排

时间 内容 2019.1.1-2019.1.18 查阅相关文献，完成外文翻译、文献综述和开题报告。

2019.2-2019.3 完成聚多巴胺在pH6.5~7.5的合成 2019.3-2019.4 聚多巴胺包裹大肠杆菌催化活性验证 2019.4-2019.5 固定化复合物材料改性 2019.5-2019.6 完成论文的写作和修改