1. 毕业设计（论文）的内容和要求

作为生命代谢过程中的重要产物，活性氧物种 (ros) 主要包含次氯酸 (hocl)、羟基自由基(oh#8226;)、过氧亚硝基阴离子(onoo-)、过氧化氢 (h2o2) 、单线态氧 (#8226;o2) 、超氧阴离子(o2#8226;-)、臭氧 (o3)、和亚硝酰(hno)等活性含氧自由基和分子，它们在生物体内的水平与机体的生理及病理状态相关。

这些ros性质通常比较活跃，能够直接与多种生物大分子作用，从而在机体的免疫反应过程中发挥着重要作用。

同时适当水平的ros对正常的生理过程亦是至关重要的，它们参与细胞生长调节、能量合成与代谢、重要物质的合成和细胞信号转导等重要生理过程。

2. 参考文献

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3. 毕业设计（论文）进程安排

1.02前 与导师会面，布置论文题目及要求 2.02-2.18 查阅资料，完成开题报告和任务书 2.18-2.25 准备实验所需药品和器材 2.25-4.00 罗丹明衍生物修饰稀土纳米晶上转换HOCl探针的合成 4.01-4.05 摸索上转换纳米探针探针的分析条件 4.06-4.20 上转换纳米探针的紫外、荧光分析实验 4.21-5.9 活细胞体外上转换发光(UCL)成像研究 5.10-5.31 数据整理，书写论文,制作PPT 6.01-6.03 准备论文答辩