1. 毕业设计（论文）的内容和要求

5-羟基糠醛是一种重要的平台分子化合物，是重要的工业中间体。

目前合成hmf最主要的方法是通过酸促反应将糖类水解制取5-羟甲基糠醛。

工业上主要使用的还是无机酸，但是无机酸易于腐蚀设备，造成环境污染，有机固体酸的成为人们研究的热点。

2. 参考文献

1 Antonetti C, Melloni M, Licursi D, et al. Microwave-assisted dehydration of fructose and inulin to HMF catalyzed by niobium and zirconium phosphate catalysts[J]. Applied Catalysis B: Environmental, 2017, 206: 364-377. 2 Gao D M, Zhao B, Liu H, et al. Synthesis of a hierarchically porous niobium phosphate monolith by a sol-gel method for fructose dehydration to 5-hydroxymethylfurfral[J]. Catalysis Science Technology, 2018. 3 Sun Y, Zhang Q, Zhang P, et al. Nitrogen-Doped Carbon-Based Acidic Ionic Liquid Hollow Nanospheres for Efficient and Selective Conversion of Fructose to 5-Ethoxymethylfurfural and Ethyl Levulinate[J]. ACS Sustainable Chemistry Engineering, 2018, 6(5): 6771-6782. 4 Karimi B, Mirzaei H M, Behzadnia H, et al. Novel ordered mesoporous carbon based sulfonic acid as an efficient catalyst in the selective dehydration of fructose into 5-HMF: the role of solvent and surface chemistry[J]. ACS applied materials interfaces, 2015, 7(34): 19050-19059. 5 Wang T, Nolte M W, Shanks B H. Catalytic dehydration of C6 carbohydrates for the production of hydroxymethylfurfural (HMF) as a versatile platform chemical[J]. Green Chemistry, 2014, 16(2): 548-572. 6 Dong K, Zhang J, Luo W, et al. Catalytic conversion of carbohydrates into 5-hydroxymethyl furfural over sulfonated hyper-cross-linked polymer in DMSO[J]. Chemical Engineering Journal, 2018, 334: 1055-1064. 7 Yang Z, Qi W, Huang R, et al. Functionalized silica nanoparticles for conversion of fructose to 5-hydroxymethylfurfural[J]. Chemical Engineering Journal, 2016, 296: 209-216. 8 Matharu A S, Ahmed S, Al Monthery B S M, et al. Novel Starbon/HACS-supported N-heterocyclic carbene-iron (III) catalyst for efficient conversion of fructose to HMF[J]. CHEMSUSCHEM, 2017. 9 K鰎ner P, Jung D, Kruse A. The effect of different Br鴑sted acids on the hydrothermal conversion of fructose to HMF[J]. Green Chemistry, 2018, 20(10): 2231-2241. 10 Galaverna R, Breitkreitz M C, Pastre J C. Conversion of d-Fructose to 5-(Hydroxymethyl) furfural: Evaluating Batch and Continuous Flow Conditions by Design of Experiments and In-Line FTIR Monitoring[J]. ACS Sustainable Chemistry Engineering, 2018, 6(3): 4220-4230. 11 Verma S, Baig R B N, Nadagouda M N, et al. Sustainable pathway to furanics from biomass via heterogeneous organo-catalysis[J]. Green Chemistry, 2017, 19(1): 164-168. 12 Dai J, Zhu L, Tang D, et al. Sulfonated polyaniline as a solid organocatalyst for dehydration of fructose into 5-hydroxymethylfurfural[J]. Green Chemistry, 2017, 19(8): 1932-1939. 13 Svenningsen G, Kumar R, Wyman C E, et al. Unifying Mechanistic Analysis of Factors Controlling Selectivity in Fructose Dehydration to 5-Hydroxymethylfurfural by Homogeneous Acid Catalysts in Aprotic Solvents[J]. ACS Catalysis, 2018, 8, 6, pp 5591?600. 14 Wang Q, Hou W, Li S, et al. Hydrophilic mesoporous poly (ionic liquid)-supported Au-Pd alloy nanoparticles towards aerobic oxidation of 5-hydroxymethylfurfural to 2, 5-furandicarboxylic acid under mild conditions[J]. Green Chemistry, 2017, 19(16): 3820-3830. 15 Marianou A A, Michailof C M, Pineda A, et al. Effect of Lewis and Br鴑sted acidity on glucose conversion to 5-HMF and lactic acid in aqueous and organic media[J]. Applied Catalysis A: General, 2018, 555: 75-87. 16 Guo J, Zhu S, Cen Y, et al. Ordered mesoporous Nb-W oxides for the conversion of glucose to fructose, mannose and 5-hydroxymethylfurfural[J]. Applied Catalysis B: Environmental, 2017, 200: 611-619.

3. 毕业设计（论文）进程安排

确认下达任务书、开题报告、合成单体、合成聚合物、表征结构等物理性质、催化反应、产物的定性与定量、整理实验数据、完善论文